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دراسة جديدة نُشرت في JCO Precision Oncology تُظهر أن اختبار Prolaris من Myriad Genetics يمكنه التنبؤ بفائدة العلاج الهرموني لدى الرجال المصابين بسرطان البروستاتا الموضعي

Myriad’s Prolaris Test is the only biomarker test to quantify the benefits of adding androgen deprivation therapy to radiation therapy1 New Study Published in JCO Precision Oncology Shows Myriad Genetics‘ Prolaris Test Can Predict Benefit of Hormone Therapy Treatment in Men with Localized Prostate Cancer

Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4)

BRISBANE, Calif., May 16, 2024 (GLOBE NEWSWIRE) — Annexon, Inc. (Nasdaq: ANNX), a clinical-stage biopharmaceutical company developing a new class of complement-based medicines for people living with devastating inflammatory-related diseases, today announced that it has granted inducement to two new non-executive employees under the terms of the 2022 Employment Inducement Award Plan. The equity awards were approved on May 11, 2024, in accordance with Nasdaq Listing Rule 5635(c)(4). Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4)

CytomX Therapeutics Announces New Employment Inducement Grants

SOUTH SAN FRANCISCO, Calif., May 16, 2024 (GLOBE NEWSWIRE) — CytomX Therapeutics, Inc. (Nasdaq: CTMX), a leader in the field of masked, conditionally activated biologics, today announced that on May 15, 2024, the Company granted two new employees options to purchase a total of 130,000 shares of the Company’s common stock at an exercise price per share equal to $1.96, which was the closing price on May 15, 2024, the date of the grants. CytomX Therapeutics Announces New Employment Inducement Grants

Krankenhausgesellschaft kritisiert neuen Klinik-Atlas

Die Deutsche Krankenhausgesellschaft (DKG) hat den Klinik-Transparenz-Atlas von Bundesgesundheitsminister Karl Lauterbach (SPD), der am Freitag offiziell vorgestellt und frei geschaltet werden soll, als irreführend und überflüssig kritisiert. „Es gibt keinen Bereich im Gesundheitswesen, der in der Qualität so transparent ist, wie die Krankenhäuser“, sagte DKG-Chef Gerald Gaß dem „Redaktionsnetzwerk Deutschland“. Schon seit über zwei Jahrzehnten […] Krankenhausgesellschaft kritisiert neuen Klinik-Atlas

Nuvalent Receives U.S. FDA Breakthrough Therapy Designation for NVL-655

CAMBRIDGE, Mass., May 16, 2024 /PRNewswire/ — Nuvalent, Inc. (Nasdaq: NUVL), a clinical-stage biopharmaceutical company focused on creating precisely targeted therapies for clinically proven kinase targets in cancer, today announced that the U.S. Food and Drug Administration (FDA) has granted breakthrough therapy designation (BTD) to NVL-655 for the treatment of patients with locally advanced or metastatic ALK-positive non-small cell lung cancer (NSCLC) who have been previously treated with two or more ALK tyrosine kinase inhibitors (TKIs). ALK rearrangements occur in up to approximately 5% of metastatic NSCLCs. At the time of diagnosis, up to 40% of these patients present with accompanying brain metastases, and approximately 50% of patients develop resistance mutations following treatment with currently available first- or second-generation ALK TKIs. There remains no clear standard of care for patients who have been previously treated with two or more ALK… 

Discover the Future of Sensory Medicine with Eye & ENT Research

Eye & ENT Research, a pioneering open-access journal, stands at the forefront of integrating ophthalmology and otolaryngology research. This innovative platform bridges the gap between basic science and clinical applications, focusing on vision, hearing, smell, and related human diseases. Our mission is clear: to advance understanding and treatment within these vital fields, offering researchers and clinicians globally the latest findings and methodologies. https://onlinelibrary.wiley.com/journal/28351088

Celiac disease: New findings on the effects of gluten

May is Celiac Disease Awareness Month. Celiac disease is a chronic autoimmune condition that occurs in around one per cent of the world’s population. It is triggered by the consumption of gluten proteins from wheat, barley, rye and some oats. A gluten-free diet protects celiac patients from severe intestinal damage. Together with colleagues, chemist Dr Verónica Dodero from Bielefeld University was able to determine new details on how certain gluten-derived molecules trigger leaky gut syndrome in celiac disease. The key finding of the study: a particular protein fragment formed in active celiac disease forms nanosized structures, the so-called oligomers, and accumulates in a gut epithelial cell model. The technical name of the molecule is 33-mer deamidated gliadin peptide (DGP). The study team has now discovered that the presence of DGP oligomers may open the tightly closed gut lining, leading to…