COBENFY represents the first new pharmacological approach to treat schizophrenia in decades, with a mechanism of action distinct from current therapies
Approval is supported by data from the EMERGENT clinical program demonstrating statistically significant reductions of schizophrenia symptoms
The safety and tolerability profile of COBENFY has been established across acute and long-term trials in schizophrenia.
COBENFY represents the first new class of medicine in several decades and introduces a fundamentally new approach to treating schizophrenia by selectively targeting M 1 and M 4 receptors in the brain without blocking D 2 receptors.
Schizophrenia is a persistent and often disabling mental illness affecting how a person thinks, feels and behaves. 5 It is estimated to impact approximately 2.8 million people in the United States. 6 Symptoms typically first appear in early adulthood and present differently in each person, making symptoms difficult to diagnose and manage. 6 While the current standard of care can be effective in managing symptoms of schizophrenia, up to 60% of people experience inadequate improvement in symptoms or intolerable side effects during therapy.
https://www.nature.com/articles/d41573-024-00155-8
