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Semaglutide and ReCET Reduce Need for Insulin Therapy in Diabetes

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A groundbreaking study presented at UEG Week 2024 investigates a novel treatment strategy for type 2 diabetes (T2D) that has the potential to significantly reduce or even eliminate the need for insulin therapy[1]. This innovative approach combines a novel procedure called ReCET (Re-Cellularization via Electroporation Therapy) with the drug semaglutide. ReCET is a procedure performed under deep sedation that aims to improve the body's sensitivity to its own insulin[1]. Following the ReCET treatment, study participants followed a two-week isocaloric liquid diet before gradually starting semaglutide, up to a dose of 1mg per week[1]. Semaglutide is a drug in the GLP-1 receptor agonist class used to treat type 2 diabetes and as a weight-loss agent[3]. It works by increasing insulin secretion, lowering glucagon release, delaying gastric emptying, and reducing appetite[4]. The… 

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ReCET with semaglutide may eliminate insulin dependency in type 2 diabetes

Groundbreaking research presented today at UEG Week 2024 reveals a promising new treatment strategy for type 2 diabetes (T2D) that could significantly reduce or even eliminate the need for insulin therapy. This innovative approach, which combines a novel procedure known as ReCET (Re-Cellularization via Electroporation Therapy) with semaglutide, resulted in the elimination of insulin therapy for 86% of patients. Globally, T2D affects 422 million people, with obesity recognised as a significant risk factor. While insulin therapy is commonly used to manage blood sugar levels in T2D patients, it can result in side effects such as weight gain and further complicate diabetes management. A need therefore exists for alternative treatment strategies. The first-in-human study included 14 participants aged 28 to 75 years, with body mass indices ranging from 24 to 40 kg/m². Each participant underwent the ReCET procedure under deep sedation,… 

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Canton of Zurich and Foundations Deepen Cooperation

The Office for Economic Affairs of the Canton of Zurich and the SwissFoundations association held their second foundation discussion. The focus was on the optimal design of cooperation. Common goals and the earliest possible exchange were identified as decisive.     The Office for Economic Affairs of the Canton of Zurich and the SwissFoundations association met on October 1st at Kraftwerk/Impact […] Canton of Zurich and Foundations deepen cooperation

ETH remains one of the world's best universities

The Swiss Federal Institute of Technology Zurich (ETH) ranks eleventh in the latest university ranking by Times Higher Education (THE). Oxford University is in first place. The Swiss Federal Institute of Technology Lausanne ranks 32nd, and the University of Zurich ranks 80th.     According to a press release, the Swiss Federal Institute of Technology Zurich (ETH) is for the third time among the world's best universities

UZH develops neural sensors for agriculture

Researchers from the University of Zurich (UZH) and the Polytechnic University of Turin are developing sensors and chips for use in agriculture. The learning neural systems are intended to measure moisture, temperature, and pH to control irrigation and fertilizer application.   Researchers from the University of Zurich (UZH) are developing a neural network that measures moisture, temperature, and pH in agricultural areas [...] UZH develops neural sensors for agriculture

Background: World Health Summit (WHS) 2024 Berlin

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The World Health Summit (WHS) 2024 will take place from October 13 to 15 in Berlin under the motto “Building Trust for a Healthier World”[1][2]. As one of the most important international platforms for global health issues, the WHS brings together over 3,000 participants from more than 100 countries annually, including leading experts from science, politics, business, and civil society[1][5]. The event is under the patronage of German Chancellor Olaf Scholz, French President Emmanuel Macron, and WHO Director-General Tedros Adhanom Ghebreyesus[1][2]. This underscores the high political relevance and international importance of the summit. Key topics of WHS 2024 include the financing of global health solutions, antibiotic resistance, strategies for women's and children's health, the connection between climate and health, the promotion of young leaders, and the use of artificial intelligence in healthcare[2][4]. These focal points reflect the most pressing global health challenges. A special highlight will be the presentation of the WHO's first funding round…

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WHO: Health also in danger in more modern countries

At the start of the World Health Summit in Berlin this Sunday, some health ministers and the WHO chief are warning of setbacks in commitment to global health in view of the many simultaneous crises. “Despite great progress in science and the rapid growth of innovations, our health is in danger, even in highly developed countries,” write German Federal Minister of Health Karl [...] Ministers and WHO: Health in danger even in more modern countries

New injectable to prevent and treat hypoglycemia

Diabetics take insulin to lower high blood sugar. However, if glucose levels drop too low—perhaps due to too much insulin or too little sugar—hypoglycemia can occur, which can lead to dizziness, cognitive impairment, seizures, or coma. To prevent and treat this condition, researchers report in ACS Central Science about encapsulating the hormone glucagon. In tests on mice, the nanocapsules were activated when blood glucose levels dropped dangerously low and quickly restored glucose levels. Glucagon is a hormone that signals the liver to release glucose into the bloodstream. It is normally administered as an injection to counteract severe hypoglycemia in diabetics. While an emergency injection of glucagon can correct blood sugar levels in about 30 minutes, formulations can be unstable and insoluble in water. In some cases, the hormone quickly degrades and clumps when mixed for injections… 

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Nursing homes restrict services due to staff shortages

63 percent of outpatient services and nursing homes have restricted their services in the past six months due to staffing issues. This is according to a preliminary analysis of a survey by the German Protestant Association for Elderly Care and Nursing (DEVAP), which "Der Spiegel" reports on. 87 percent of the surveyed outpatient providers stated that they had to turn away new clients. 47 [...] Nursing homes restrict services due to staff shortages

Blood values: Blood test detects lung cancer

New research findings show promising approaches for the early detection of lung cancer through blood tests. These could play an important role in the future in identifying high-risk individuals and improving survival rates. Inflammatory markers in the blood Scientists at the German Cancer Research Center (DKFZ) have investigated whether inflammatory markers in the blood can improve the predictive accuracy of lung cancer risk. They analyzed a panel of 92 biomarkers, including cytokines and interleukins, in blood samples from participants in the ESTHER study[1]. The results showed that the determination of these inflammatory markers can significantly improve lung cancer risk prediction. The combination of marker analysis with conventional risk calculations led to more precise predictions[1]. This could help to better identify high-risk individuals who could benefit from CT-based early detection screening. Lipid markers in the blood A study by Chinese researchers at Peking University People's Hospital has developed a promising approach for the early detection of early-stage lung cancer. The scientists identified nine specific fats (lipids) that are characteristic of lung tumors[2].… 

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