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Viele Tumore schütten Prostaglandin E2 aus. So verhindern sie, dass sich stammzellartige T-Zellen zu Zellen ausdifferenzieren, die den Krebs angreifen. Dr. Jan Böttcher (l.) und Erstautor Sebastian Lacher schildern in "Nature" den Mechanismus dahinter. | Quelle: Astrid Eckert / TUM | Copyright: Astrid Eckert

Abwehr der Tumorzellen geknackt

Prostaglandin E2 ist das molekulare Schutzschild jeder Tumorzelle: Der Botenstoff wappnet die Krebszellen gegen potente Immuntherapien. Jetzt haben Wissenschaftler den Mechanismus verstanden – und könnten dadurch die Tumorabwehr brechen.

Cancer Diagnostic Market 2030. copyright: SNS Insider

Cancer Diagnostics Market to Hit USD 334.64 Billion by 2030

According to the latest market analysis by SNS Insider, the Cancer Diagnostics market size was valued at USD 193.31 billion in 2022 and is projected to reach USD 334.64 billion by 2030, with a robust Compound Annual Growth Rate (CAGR) of 7.1% over the forecast period of 2023-2030. Cancer diagnostics play a pivotal role in the detection, diagnosis, staging, and monitoring of cancer patients, enabling healthcare providers to make informed treatment decisions, personalize therapy regimens, and improve patient outcomes. With advancements in genomics, proteomics, liquid biopsy, molecular imaging, and artificial intelligence (AI), cancer diagnostics have evolved from traditional histopathology and imaging techniques to comprehensive molecular profiling and non-invasive screening methods, revolutionizing the approach to cancer care and management. Market Report Scope & Overview Cancer diagnostics represent a pivotal aspect of modern healthcare, encompassing a wide array of techniques and methodologies aimed at… 

Lymphknotenbefall bei Brustkrebs: Bestrahlung hilft

Eine Bestrahlung der Lymphabflusswege senkt die Rezidivraten und verbessert das Gesamtüberleben bei Brustkrebspatientinnen mit Lymphknotenbefall. Zu diesem Schluss kommt eine Metaanalyse der „Early Breast Cancer Trialists‘ Collaborative Group“ (EBCTCG).

INTERVIEW zum Kinderkrebstag: „Die Familien befinden sich in einer Ausnahmesituation“

Mehr als 2.000 Kinder und Jugendliche in Deutschland erkranken jährlich an Krebs. Wenn ein Kind oder ein Elternteil die Diagnose Krebs erhält, hat dies Auswirkungen auf das gesamte Familienleben. Das Universitäre Cancer Center Hamburg (UCCH) des Universitätsklinikums Hamburg-Eppendorf (UKE) hat daher eine psychosoziale Beratungsstelle für an Krebs erkrankte Kinder, Jugendliche und junge Erwachsene sowie deren Familien eingerichtet. Anlässlich des Internationalen Kinderkrebstags am 15. Februar informiert Priv.-Doz. Dr. Gabriele Escherich, Oberärztin in der Klinik für Pädiatrische Hämatologie und Onkologie des UKE, über das neu geschaffene Angebot.

Foto: Pexels.com

BD Partners with Techcyte to Offer AI-Powered Cervical Cancer Screening

  • AI

According to the World Health Organization, cervical cancer was responsible for an estimated 342,000 deaths worldwide in 2020. Limited access to screening is one reason why people still die from cervical cancer. BD supports screening with its human papillomavirus (HPV) test and the Surepath liquid-based Pap test. Although HPV tests are more sensitive, according to the company, it expects Pap tests to "continue to play an important diagnostic role as programs transition to the new standard of care. Techcyte's system is compatible with several liquid-based cytology preparations, including Surepath. Traditionally, cytotechnologists and pathologists viewed glass slides under a microscope. To use the Techcyte system, technologists prepare slides with systems like Surepath and scan them to create digital files. The AI algorithm then identifies cells with features that suggest they may be diagnostically relevant."

Untire app now prescribable for breast cancer

The health app Untire has been provisionally included in the directory of Digital Health Applications (DiGA) of the Federal Institute for Drugs and Medical Devices (BfArM). It is the first DiGA specifically for tumor-associated fatigue. Effective immediately, doctors and psychotherapists can prescribe this digital therapy to their breast cancer patients on prescription. Breast cancer (mammary carcinoma) is the most common cancer in women in Germany. More than 70,000 people fall ill with it each year, and the 10-year prevalence is 570,900.[1] The most common accompanying condition of the disease and its treatment is so-called tumor-associated fatigue (CRF), also known as cancer-related fatigue, which significantly impairs the general well-being of those affected. There is currently no drug treatment available. Untire is the first DiGA to help breast cancer patients reduce their exhaustion. In the Netherlands and Great Britain, 40,000 cancer patients are already using the app. With its inclusion in the BfArM's DiGA directory, Untire can...