Poorly functioning blood vessels lead to muscle wasting in cancer
Dysfunctional blood vessels in muscles may be responsible for the muscle weakness and weight loss experienced by most cancer patients. This is according to a new study by researchers at the University of Illinois Chicago. The discovery could help cancer survivors regain muscle strength, contributing to better outcomes for these patients, said Dr. Jalees Rehman, senior author of the new paper and Benjamin J. Goldberg Professor and Head of the Department of Biochemistry and Molecular Genetics at the College of Medicine. Up to 80% of cancer patients suffer from muscle wasting, known as cachexia, a debilitating complication characterized by extreme fatigue, weight loss, and loss of appetite. "It is one of the main drivers of poor outcomes for cancer survivors when they are no longer able to perform their daily activities due to the loss of significant muscle strength," said Rehman, who is also co-leader of the Translational Oncology Research…

