The team led by PD Dr. Markus Chmielewski at the Center for Molecular Medicine Cologne (ZMMK) presents a new strategy for making CAR T-cell-based immunotherapy more effective and safer. The study was published in the journal Cell Reports Medicine under "An anti-CD19/CTLA-4 switch improves efficacy and selectivity of CAR T cells targeting CD80/86-upregulated DLBCL."
Original publication:
https://www.sciencedirect.com/science/article/pii/S2666379124000442
